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Adjuvant Combo Boosts Survival in Resected Pancreatic Cancer


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Postoperative treatment of pancreatic cancer with nab-paclitaxel (Abraxane) and gemcitabine improved survival by more than 4 months as compared with gemcitabine alone, long-term follow-up from a randomized trial showed.
Median overall survival (OS) was 41.8 months with the combination versus 37.7 months with single-agent gemcitabine. The combination led to a 7% absolute improvement in 5-year OS.
The survival advantage remained consistent across a prespecified subgroup analysis, reported Margaret A. Tempero, MD, of the University of California San Francisco, during the virtual World Congress on Gastrointestinal Cancer. OS was a secondary endpoint of the randomized phase III APACT trial, which did not meet the primary endpoint of disease-free survival (DFS). ....

Charles Bankhead , Margareta Tempero , Thomas Seufferlein , University Of California San Francisco , University Of Ulm , World Congress On Gastrointestinal Cancer , California San Francisco , World Congress , Medpage Today , சார்லஸ் வங்கித் தலை , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா சான் பிரான்சிஸ்கோ , பல்கலைக்கழகம் ஆஃப் அல்ம் , உலகம் காங்கிரஸ் ஆன் இரைப்பை குடல் புற்றுநோய் , கலிஃபோர்னியா சான் பிரான்சிஸ்கோ , உலகம் காங்கிரஸ் ,