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New Insights Into Hormone's Action Could Help in Battle Against Prostate Cancer


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New Insights Into Hormone’s Action Could Help in Battle Against Prostate Cancer
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect genetic activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells – and cancer – interact with androgen. ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Bryce Paschal , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , School Of Medicine Department Biochemistry , National Institutes Of Health Cancer Institute , Cancer Center , University Of Virginia Public , Molecular Genetics , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Virginia Public , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,

New insights into androgen's action could boost battle against prostate cancer


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IMAGE: Bryce M. Paschal, PhD, of the University of Virginia School of Medicine s Department of Biochemistry and Molecular Genetics, has unveiled a new mechanism for how the androgen hormone regulates communication.
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Credit: Angela Paschal
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells - an ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , National Institutes Of Health Cancer Institute , Cancer Center , Virginia School , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Medicine Health , Prostate Cancer , Internal Medicine , Sex Linked Conditions , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,