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University of Virginia reveals new prostate cancer study


University of Virginia reveals new prostate cancer study
University of Virginia reveals new prostate cancer study
By Dominga Murray | May 18, 2021 at 8:20 PM EDT - Updated May 18 at 8:20 PM
CHARLOTTESVILLE, Va. (WVIR) - Researchers at the University of Virginia Cancer Center just released a discovery that could boost treatment efforts for prostate cancer.
The findings focus on how hormones called androgens act on our cells. It sheds light on how these hormones interact inside the cell affecting gene activity.
The cells communicate through something called signal transduction pathways and understanding this better can lead to more effective treatments.
“This can help us understand why certain prostate cancer therapies fail. It can also reveal new drug targets in prostate cancer,” Bryce M. Paschal of the UVA School of Medicine’s department of biochemistry and molecular genetics said. ....

Brycem Paschal , University Of Virginia Cancer Center , School Of Medicine Department , Virginia Cancer Center , University Of Virginia , Cancer Treatment , Prostate Cancer , Brycem Paschal , பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா புற்றுநோய் மையம் , பள்ளி ஆஃப் மருந்து துறை , வர்ஜீனியா புற்றுநோய் மையம் ,

New Insights Into Hormone's Action Could Help in Battle Against Prostate Cancer


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New Insights Into Hormone’s Action Could Help in Battle Against Prostate Cancer
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect genetic activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells – and cancer – interact with androgen. ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Bryce Paschal , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , School Of Medicine Department Biochemistry , National Institutes Of Health Cancer Institute , Cancer Center , University Of Virginia Public , Molecular Genetics , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Virginia Public , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,

New insights into androgen's action could boost battle against prostate cancer


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IMAGE: Bryce M. Paschal, PhD, of the University of Virginia School of Medicine s Department of Biochemistry and Molecular Genetics, has unveiled a new mechanism for how the androgen hormone regulates communication.
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Credit: Angela Paschal
Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.
The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So scientists are eager to better understand how our cells - an ....

Kasey Jividen , Luke Oostdyk , Nicholase Sherman , Brycem Paschal , Bartlomiej Remlein , Tarek Abbas , Yasin Pourfarjam , Teddy Kamata , Natalia Dworak , David Wotton , Kwon Kim , Nature Communications , National Institutes Of Health Cancer Institute , Cancer Center , Virginia School , Chun Song Yang , In Kwon Kim , National Institutes , National Cancer Institute , Medicine Health , Prostate Cancer , Internal Medicine , Sex Linked Conditions , தரெக் அப்பாஸ் , டேவிட் வோட்டன் , இயற்கை தகவல்தொடர்புகள் ,