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Science News | Scientists Use Paleogenomics to Elucidate 10,000 Years of Immune System Evolution

Get latest articles and stories on Science at LatestLY. Scientists from the Institut Pasteur, Universite Paris Cite, the CNRS and the College de France have used paleogenomics to trace 10,000 years of human immune system evolution. They analyzed the genomes of more than 2,800 individuals who lived in Europe over the past ten millennia. They were able to date the increase in the frequency of most of the mutations that are advantageous in defending against pathogens to after the Bronze Age, 4,500 years ago. The scientists also observed that mutations conferring a higher risk of developing inflammatory disorders have become more frequent over the past 10,000 years. These enlightening results on the effects of natural selection on immunity genes were published in the journal Cell Genomics on January 13, 2023. Science News | Scientists Use Paleogenomics to Elucidate 10,000 Years of Immune System Evolution. ....

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