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Takeda (TAK) and Arrowhead (ARWR) Report Topline Results from SEQUOIA Phase 2 Study of Fazirsiran
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Arrowhead and Takeda Announce Topline Results from SEQUOIA Phase 2 Study of Fazirsiran in Patients with Alpha-1 Antitrypsin Deficiency-Associated Liver Disease
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1. Rare mutations in CIDEB are associated with a decreased risk of developing liver cirrhosis. 2. Further, rare mutations in CIDEB are associated with a decreased risk of nonalcoholic fatty liver disease. Evidence Rating Level: 1 (Excellent) Study Rundown: For patients with obesity and nonalcoholic fatty liver disease, the risk of progression to steatohepatitis and
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