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Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system. ....

Amanda Gavin , Xueyong Zhu , Fangkun Luan , Ziqi Feng , Jeanne Matteson , Jenny Tran , Ian Wilson , David Nemazee , Linghang Peng , National Institutes Of Health , Department Of Immunology , Computational Biology At Scripps Research , Scripps Research Institute , Department Of Integrative Structural , Scripps Research , Meng Yuan , Integrative Structural , Computational Biology , Deli Huang , National Institutes , Skaggs Institute , Chemical Biology , Structural Biology , Lzheimer 39s Disease , Immune System , Lupus Erythematosus ,

'Unheard of in structural biology': New enzyme models reveal disease insights

'Unheard of in structural biology': New enzyme models reveal disease insights
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Ziqi Feng , Fangkun Luan , Linghang Peng , Ian Wilson , Xueyong Zhu , Amanda Gavin , Jenny Tran , David Nemazee , Jeanne Matteson , Department Of Integrative Structural , Scripps Research , Computational Biology At Scripps Research , Department Of Immunology , Meng Yuan , Integrative Structural , Computational Biology , Deli Huang ,

Revolutionary Enzyme Models Unveil Disease Insights

Revolutionary Enzyme Models Unveil Disease Insights
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Ian Wilson , Amanda Gavin , Fangkun Luan , Jeanne Matteson , Ziqi Feng , Jenny Tran , Xueyong Zhu , Linghang Peng , David Nemazee , Scripps Research Translational Institute , Department Of Integrative Structural , Department Of Immunology , National Institutes Of Health , Skaggs Graduate School , Computational Biology At Scripps Research , Scripps Research , Meng Yuan , Integrative Structural , Computational Biology , Deli Huang , National Institutes , Skaggs Institute , Chemical Biology ,

Mutation-mapping tool could yield stronger COVID boosters, universal vaccines

Mutation-mapping tool could yield stronger COVID boosters, universal vaccines
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Paul Steiner , Timothy Whitehead , Shawn Barman , Monica Kirby , Kayla Sprenger , Irene Francino Urdaniz , Cyrus Haas , Linghang Peng , Joseph Jardine , Alison Leonard , Fangzhu Zhao , Emily Rhodes , Scripps Research Institute , Centers For Disease , Vaccine Initiative , Cell Reports , Disease Control , Francino Urdaniz , Biological Engineering , பால் ஸ்டீனர் , தீமோத்தேயு வைட்ஹெட் , கயில ஸ்ப்ரெஞ்சர் , ஜோசப் ஜார்டின் , அலிசன் லியோனார்ட் , எமிலி ரோட்ஸ் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி நிறுவனம் ,

Versatile coronavirus antibody may be starting point for broader-acting vaccines

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LA JOLLA, CA Even before the COVID-19 pandemic, most people in the United States already had been sick with a coronavirus, albeit a far less dangerous one. That s because at least four coronaviruses in the same general family as SARS-CoV-2 cause the benign yet annoying illness known as the common cold.
In a new study that appears in
Nature Communications, scientists from Scripps Research investigated how the immune system s previous exposure to cold-causing coronaviruses impact immune response to COVID-19. In doing so, they discovered one cross-reactive coronavirus antibody that s triggered during a COVID-19 infection.
The findings will help in the pursuit of a vaccine or antibody treatment that works against most or all coronaviruses, says senior author Raiees Andrabi, PhD, an investigator in the Department of Immunology and Microbiology. ....

United States , Nathan Beutler , Thomas Rogers , Davey Smith , James Ricketts , James Voss , David Nemazee , Mara Parren , Sean Callaghan , Linghang Peng , Linlin Yang , Andrew Ward , Jon Cassell , Raiees Andrabi , Jonathan Torres , Dennis Burton , Fabio Anzanello , Sirena Vargas , Caroline Ignacio , Nature Communications , Antibody Center , Jamesb Pendleton Charitable , Melinda Gates Foundation , Scripps Research , Mary Tu Foundation , Department Of Immunology ,