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Understanding the Impact of COSMIC-311 and Sequencing in DTC

Marcia Brose, MD, examines data from the COSMIC-311 study, emphasizing the importance of promptly initiating second-line therapy for patients who have progressed on first-line treatments. ....

Optimizing Therapy , Cosmic 311 , Braf Mutations , Braf Inhibitor , Braf V600e , Tumor Shrinkage , Ocular Toxicities , Cardiac Toxicities ,

HCC Trials: Insights from the LAUNCH, EMERALD-1, and LEAP-012 Trials

Medical experts discuss the LAUNCH study, EMERALD-1, and LEAP-012 trials, providing updates on the progress and findings that influence the treatment paradigm for hepatocellular carcinoma. ....

Tyrosine Kinase Inhibitors , Unresectable Hepatocellular Carcinoma , Hepatocellular Carcinoma , Transarterial Chemoembolization , Launch Study , Emerald 1 Study ,

KEYNOTE-B61: Lenvatinib Plus Pembrolizumab in Non–Clear Cell RCC

Focusing on the KEYNOTE-B61 trial evaluating lenvatinib plus pembrolizumab in the first line, a panel of medical oncologists react to clinical trial data on combination regimens in non–clear cell renal cell carcinoma. ....

Advanced Renal Cell Carcinoma , Lenvatinib Plus Pembrolizumab , Clear Cell , Renal Cell Carcinoma , Advanced Rcc , Non Clear Cell Rcc , Non Clear Cell Renal Carcinoma , Keynote B61 ,

Dr Merchan on Key Data Supporting Pembrolizumab-Based Regimens in Advanced RCC

Jaime R. Merchán, MD, discusses the role of pembrolizumab plus axitinib or lenvatinib in previously untreated advanced renal cell carcinoma. ....

Jaimer Merch , Division Of Medical Oncology , Department Of Medicine , Clinical Trials Program , University Of Miami Health System , Sylvester Comprehensive Cancer Center , Clinical Oncology Research Program , Medical Oncology , Trials Program , Miami Health System , Cancers Symposium , Advanced Rcc ,

Extended Follow-Up Confirm Efficacy of First-Line Pembrolizumab/Lenvatinib Combo in Advanced Non–Clear Cell RCC

Frontline pembrolizumab plus lenvatinib continues to show benefit vs historical controls in advanced non–clear cell renal cell carcinoma. ....

Martinh Voss , International Metastatic Renal Cell Carcinoma Database Consortium , Merck Co Inc , Merck Sharp Dohme , Cancers Symposium , Genitourinary Medical Oncology Service , Memorial Sloan Kettering Cancer Center , Merck Sharp , Rhas Y , Non Clear Cell Rcc , Renal Cell Carcinoma , Phase 2 Keynote B61 Trial , 2024 Genitourinary Cancers Symposium , First Line Pembrolizumab Plus Lenvatinib ,