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Indivior Announces Publication Demonstrating that OPVEE® (nalmefene) Nasal Spray Rapidly Reverses Effects of Opioid-Induced Respiratory Depression in Head-to-Head Study Against Intranasal Naloxone

/PRNewswire/ Indivior PLC (LSE/Nasdaq: INDV) today announced results from a pharmacodynamic study demonstrating that OPVEE® rapidly reverses opioid-induced. ....

United States , Lennonh Ventilatory , Christian Heidbreder , Health Statistics , Wiley Online Library , National Center , Prnewswire Indivior , Clinical Pharmacology , Induced Respiratory Depression , Healthy Volunteers , Intranasal Nalmefene , Intranasal Naloxone , Online Library , Chief Scientific Officer , Recurrent Respiratory , Central Nervous System Depression , Partial Agonists , Severe Opioid Withdrawal , Opioid Overdose , Prescribing Information , Accessed February , Indivior Plc , Health Care Amp Hospitals , Medical Pharmaceuticals , Clinical Trials Amp Medical Discoveries ,

Indivior Announces Publication Demonstrating that OPVEE® (nalmefene) Nasal Spray Rapidly Reverses Effects of Opioid-Induced Respiratory Depression in Head-to-Head Study Against Intranasal Naloxone

This head-to-head pharmacodynamic study in healthy volunteers examined the ability of both OPVEE and intranasal naloxone to reverse opioid-induced respiratory depression, which is the shallow and slow breathing associated with an opioid overdose In this model, OPVEE 2.7mg reversed respiratory depression to 95% of pre-opioid baseline within 5 minutes; a similar reversal following a 4 […] ....

United States , Christian Heidbreder , Lennonh Ventilatory , Health Statistics , National Center , Wiley Online Library , Clinical Pharmacology , Induced Respiratory Depression , Healthy Volunteers , Intranasal Nalmefene , Intranasal Naloxone , Chief Scientific Officer , Recurrent Respiratory , Central Nervous System Depression , Partial Agonists , Severe Opioid Withdrawal , Opioid Overdose , Prescribing Information , Accessed February ,