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This Mutation May Be The Key Driver Of Human Aging

A study in Science has tied the aging process to the deterioration of tightly packaged bundles of cellular DNA known as heterochromatinand say that the genetic mutations underlying Werner syndrome, a disorder that leads to premature aging and death, results in the deterioration of these bundles. ....

United States , Juan Carlos Izpisua Belmonte , Fuquan Yang , Jiping Yang , Ruijun Bai , Fei Yi , Emi Aizawa , Jingyi Li , Xiaoyu Li , Junzhi Zhou , Shunlei Duan , Xiuling Xu , April Goebl , Huize Pan , Keiichiro Suzuki , Yayu Wang , Izpisua Belmonte , Liang Shi , Weiqi Zhang , Xiaomeng Liu , Guang Hui Liu , Alejandro Ocampo , Concepcion Rodriguez Esteban , Rupa Devi Soligalla , Pradeep Reddy , Zimei Wang ,

Breast Cancer Cells Evade Immune Surveillance and Survive in Lymph Nodes: Study

Breast Cancer Cells Evade Immune Surveillance and Survive in Lymph Nodes: Study
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Study sheds light on how breast cancer cells

Study sheds light on how breast cancer cells
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United States , New York , Dennis Jones , Hengbo Zhou , Lutz Menzel , Meghanj Omelia , Ethelr Pereira , Jan Willem Van Wijnbergen , Patrik Andersson , Timothyp Padera , Zohreh Amoozgar , Ashwins Kumar , Ilgin Ergin , Charlie Chung , Satoru Morita , Jessicam Posada , Sampurna Chatterjee , Peigen Huang , Semir Beyaz , Mark Foundation For Cancer Research , Chan Zuckerberg Initiative Silicon Valley Community Foundation , Research Scholar , Harvard Medical School , Northwell Health Affiliation , York Genome Center , Metavivor Foundation ,

Rice lab uncovers dynamics behind protein crucial in breast cancer

Rice lab uncovers dynamics behind protein crucial in breast cancer
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Carlos Bueno , Shikai Jin , Garegin Papoian , Peter Wolynes , Gustavo Raskosky Rice University , Leilay Mathers Charitable Foundation , University Of Maryland , Proceedings Of The National Academy Sciences , National Science Foundation , Rice University , National Academy , Xun Chen , Bullard Welch Foundation Professor , Theoretical Biological Physics , Critical Assessment , Protein Structure Prediction , National Science , Charitable Foundation , Welch Chair ,

New CRISPR-based tool inserts large DNA sequences at desired sites in cells

Building on the CRISPR gene-editing system, MIT researchers designed a new tool that can snip out faulty genes and replace them with new ones. The new technique, PASTE, could hold promise for treating diseases that are caused by defective genes with a large number of mutations, such as cystic fibrosis. ....

United States , Jonathan Gootenberg , Eleonora Ioannidi , Matthew Yarnall , Rohan Krajeski , K Lisa Yang , Omar Abudayyeh , Hocke Tan Center , Cystic Fibrosis Foundation Pioneer Grant , Harvey Family Foundation , Mcgovern Institute Neurotechnology Program , Mcgovern Institute For Brain Research , Swiss National Science Foundation Postdoc Mobility Fellowship , Us National Institutes Of Health , Mcgovern Institute , Leilay Mathers Charitable Foundation , University Of California At San Diego , Mcgovern Fellow , Govern Institute , Programmable Addition , Site Specific Targeting Elements , Prashant Mali , San Diego , Molecular Therapeutics , Charitable Foundation , Seed Fund ,