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Indian-origin scientist spots genes that fight Covid-19 infection


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Indian-origin scientist spots genes that fight Covid-19 infection
A team of US scientists, led by an Indian-origin researcher, has identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes Covid-19.
According to Sumit K. Chanda, professor and director of the Immunity and Pathogenesis Programme at Sanford Burnham Prebys Medical Discovery Institute, the scientists have gained new insights into how the virus exploits the human cells it invades.
We are still searching for its Achille s Heel so that we can develop optimal antivirals, Chanda said in a paper published in the journal Molecular Cell.
Knowing which genes help control viral infection can greatly assist researchers understanding of factors that affect disease severity and also suggest possible therapeutic options. ....

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Indian-origin scientist spots genes that fight Covid infection


Indian-origin scientist spots genes that fight Covid infection
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Indian-origin scientist spots genes that fight Covid infection.. Image Source: IANS News
New York, April 17 : A team of US scientists, led by an Indian-origin researcher, has identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes Covid-19.
According to Sumit K. Chanda, professor and director of the Immunity and Pathogenesis Programme at Sanford Burnham Prebys Medical Discovery Institute, the scientists have gained new insights into how the virus exploits the human cells it invades.
We are still searching for its Achille s Heel so that we can develop optimal antivirals, Chanda said in a paper published in the journal Molecular Cell. ....

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Indian-origin scientist spots genes that fight Covid infection - www.indianweekender.co.nz

Indian-origin scientist spots genes that fight Covid infection - www.indianweekender.co.nz
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COVID-19: Scientists identify human genes that fight infection


Credit: Dotted Yeti
LA JOLLA, CALIF. - April 16, 2021 - Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers understanding of factors that affect disease severity and also suggest possible therapeutic options. The genes in question are related to interferons, the body s frontline virus fighters.
The study was published in the journal
Molecular Cell.
We wanted to gain a better understanding of the cellular response to SARS-CoV-2, including what drives a strong or weak response to infection, says Sumit K. Chanda, Ph.D., professor and director of the Immunity and Pathogenesis Program at Sanford Burnham Prebys and lead author of the study. We ve gained new insights into how the virus exploits the human cells it invades, but we are still searching for its Achille s heel so that we can develop optimal ....

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'Immune cop': La Jolla scientists identify the lungs' sensor that detects virus that causes COVID-19


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Scientists at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla say they have identified the sensor in human lungs that detects SARS-CoV-2, the virus that causes COVID-19, and signals the body to mount an antiviral response. The discovery may lead to improved treatment for those diagnosed with the disease.
The sensor in the lungs, called MDA-5, was found to be “the immune cop that’s tasked to keep an eye out for SARS-CoV-2 and call for backup,” said Sumit Chanda, director of the immunity and pathogenesis program at SBP and senior author of the study.
“MDA-5 recognizes replicating viruses in lung cells and activates interferon,” Chanda said. Interferon, a signaling protein released by cells in the immune system, is “the body’s own frontline defender against viral invasion,” he said. ....

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