People who experience a type of stroke linked with nearly half of all dementias could be treated for the first time by repurposing two cheap and common drugs, a trial shows.
A combination of two drugs showed promising phase 2 results, including a reduction in cognitive impairment in patients with lacunar stroke, and may be a potential new approach to small vessel disease.
A study of two widely used cardiovascular medications cilostazol and isosorbide mononitrate in more than 350 patients confirmed the two medications were well-tolerated and safe for people who have experienced a stroke in a small blood vessel deep in the brain.