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Eureka Advances New Chemical Method for Targeted RNA Medicine miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
New chemical method advances toward targeted RNA medicine sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
New chemical method advances toward targeted RNA medicine phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
For millennia, DNA has played a central role in storing each cell's genetic information and consists of strands with a specific sequence of four different building blocks. These DNA strands are copied by the cell at each cell division in an extremely well-orchestrated way, but amazingly, this sophisticated machinery is governed by very simple rules. ....
Oligonucleotides, or sequences produced by DNA, are the stars when it comes to all the sci-fi things manufactured DNA can do. It is the process that makes them which can go sideways. This process needs phosphoramidites, which tend to be unstable, for setting off the necessary reactions that create oligonucleotides. Temperatures over -4 degrees Fahrenheit threaten their stability. Unfortunately, there is no way to cool them down with the instruments used in DNA synthesis. This can mean they degrade before they are ever put to use. Chemists Kurt Gothelf, Troels Skrydstrup and Alexander Sandahl, who co-led a study recently published in ....