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Working under a Health Canada research license, the
Aging-US authors developed over 800 new
C. sativa cultivars and hypothesized that high-CBD
C. sativa extracts may be used to down-regulate ACE2 expression in target COVID-19 tissues.
Using artificial 3D human models of oral, airway and intestinal tissues, they identified 13 high-CBD
C. sativa extracts that decrease ACE2 protein levels.
Some
C. sativa extracts down-regulate serine protease TMPRSS2, another critical protein required for SARS-CoV-2 entry into host cells.
While their most effective extracts require further large-scale validation, their study is important for future analyses of the effects of medical cannabis on COVID-19. The extracts of their most successful novel high-CBD ....

Olga Kovalchuk , Igor Kovalchuk , Kovalchuk Research Team , Impact Journals , Research Output , Health Canada , Cancer Genome Atlas , Functional Annotation , Mammalian Genome Cap Analysis , Gene Expression , Chemistry Physics Materials Sciences , Medicine Health , Policy Ethics , தாக்கம் பத்திரிகைகள் , ஆராய்ச்சி ஔட்‌புட் , ஆரோக்கியம் கனடா , புற்றுநோய் மரபணு அட்லஸ் , கீந் வெளிப்பாடு , வேதியியல் இயற்பியல் பொருட்கள் அறிவியல் , மருந்து ஆரோக்கியம் , பாலிஸீ நெறிமுறைகள் ,