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Senolytics reduce inflammation, illness, and mortality from COVID in older mice Mayo Clinic researchers and colleagues at the University of Minnesota showed that COVID-19 exacerbates the damaging impact of senescent cells in the body. In preclinical studies, the senolytic drugs discovered at Mayo significantly reduced inflammation, illness, and mortality from COVID infection in older mice. The findings appear in the journal Science. Senescent cells (damaged or non-functioning cells that persist in the body) contribute to many aspects of aging and illness, including inflammation and multiple chronic diseases. Based on the Amplifier/Rheostat Hypothesis of senescent cells developed at Mayo, the researchers sought to discover how COVID-19 causes much higher mortality in the elderly and chronically-ill. They showed that human senescent cells have an amplified response to the SARS spike protein, provoking increased production of factors causing inflammation and tissue dam ....
Kogod family supports medical education center at MDI Hospital December 11, 2020 on News BAR HARBOR Mount Desert Island Hospital has announced that Bob and Arlene Kogod of Washington, D.C., and Seal Harbor have made a pledge to support rural medical education on MDI. “The Kogod Family Center for Medical Education, with its innovative educational curriculum, will position Mount Desert Island Hospital as a transformational leader in rural medical education,” said Arthur J. Blank, president/CEO of MDI Hospital. “The Kogod Center will proudly anchor the future of MDI Hospital’s Medical Education programs and offer dedicated student housing and conference space for the next generation of medical providers on MDI.” ....