Kogod Center On News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Senolytics reduce inflammation, illness, and mortality from COVID in older mice
Mayo Clinic researchers and colleagues at the University of Minnesota showed that COVID-19 exacerbates the damaging impact of senescent cells in the body. In preclinical studies, the senolytic drugs discovered at Mayo significantly reduced inflammation, illness, and mortality from COVID infection in older mice. The findings appear in the journal
Science.
Senescent cells (damaged or non-functioning cells that persist in the body) contribute to many aspects of aging and illness, including inflammation and multiple chronic diseases. Based on the Amplifier/Rheostat Hypothesis of senescent cells developed at Mayo, the researchers sought to discover how COVID-19 causes much higher mortality in the elderly and chronically-ill. They showed that human senescent cells have an amplified response to the SARS spike protein, provoking increased production of factors causing inflammation and tissue dam ....

Tamar Tchkonia , James Kirkland , Emily Henderson , University Of Minnesota , Kogod Center On , Kogod Center , Mayo Clinic , Ars Cov 2 , ஜேம்ஸ் கர்க்‌ல்யாஂட் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மினசோட்டா , கோகோட் மையம் ஆன் , கோகோட் மையம் , மயோ சிகிச்சையகம் ,