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IR imaging-based AI offers a label-free and automated approach to identify lung tumor types


IR imaging-based AI offers a label-free and automated approach to identify lung tumor types
Infrared spectroscopy can automatically distinguish between various types of lung cancer and genetic mutations, allowing quick and reliable statements to be made regarding prognosis and treatment decisions.
The prognosis and effective therapies differ based on the type of lung cancer. While it previously took several days to precisely determine the underlying mutation, a research team at the Centre for Protein Diagnostics (PRODI) at Ruhr-Universität Bochum (RUB) has been able to reliably perform this determination in just one step using a combination of quantum cascade laser-based infrared microscopy and artificial intelligence. The examined tissue does not need to be marked for this. The analysis only takes around half an hour. “This is a major step that shows that infrared imaging can be a promising methodology in future diagnostic testing and treatment prediction,” says Prof ....

United States , Nina Goertzen , Klaus Gerwert , Emily Henderson , Centre For Protein Diagnostics , Pathological Anatomy At University Hospital Cologne , Protein Diagnostics , Professor Klaus Gerwert , American Journal , General Pathology , Pathological Anatomy , University Hospital , Frederik Gro , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , மையம் க்கு ப்ரோடீந் பரிசோதனை , ப்ரோடீந் பரிசோதனை , அமெரிக்கன் இதழ் , ஜநரல் நோயியல் , நோயியல் உடற்கூறியல் , பல்கலைக்கழகம் மருத்துவமனை , ஃப்ரெடர்ரிக் க்ரோ ,

Cancer-promoting Ras protein exists in a pair within cells


Credit: PRODI/ Till Rudack
Researchers from Bochum and Osnabrück have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer. With the help of fluorescence markings, they have demonstrated that the protein is deposited in a pair at the cell membrane, and with the very structure that they predicted in theory back in 2012. The team from the Bochum Center for Protein Diagnostics (PRODI) hopes that these findings will open up a new approach for the development of cancer medications. The researchers from Ruhr-Universität Bochum (RUB) and Osnabrück University published the results in the ....

Klaus Gerwert , Group Leader , Bochum Center , Protein Diagnostics , Chemical Science , Professor Klaus Gerwert , Founding Director , Till Rudack , Associate Professor , Project Group Leader , Biomechanics Biophysics , குழு தலைவர் , ப்ரோடீந் பரிசோதனை , இரசாயன அறிவியல் , ஸ்தாபகம் இயக்குனர் , இணை ப்ரொஃபெஸர் ,