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Almost all attempts to use the Ras protein as a point of attack for medications have so far failed. New knowledge concerning its structure is raising hopes of options in the development of medications. ....
Credit: PRODI/ Till Rudack Researchers from Bochum and Osnabrück have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer. With the help of fluorescence markings, they have demonstrated that the protein is deposited in a pair at the cell membrane, and with the very structure that they predicted in theory back in 2012. The team from the Bochum Center for Protein Diagnostics (PRODI) hopes that these findings will open up a new approach for the development of cancer medications. The researchers from Ruhr-Universität Bochum (RUB) and Osnabrück University published the results in the ....