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Key immunity characteristics of diverse stages of brucellosis in rural population from Inner Mongolia, China | Infectious Diseases of Poverty

Brucellosis poses a serious threat to human and animal health, particularly in developing countries such as China. The Inner Mongolia Autonomous Region is one of the most severely brucellosis-endemic provinces in China. Currently, the host immune responses functioning to control Brucella infection and development remain poorly understood. The aim of this study is to further clarify the key immunity characteristics of diverse stages of brucellosis in Inner Mongolia. We collected a total of 733 blood samples from acute (n = 137), chronic (n = 316), inapparent (n = 35), recovery (n = 99), and healthy (n = 146) groups from the rural community of Inner Mongolia between 2014 and 2015. The proportions of CD4+, CD8+, Th1, Th2, and Th17 T cells in peripheral blood and the expression of TLR2 and TLR4 in lymphocytes, monocytes and granulocytes were examined using flow cytometry analysis. The differences among the five groups were compare ....

United States , Inner Mongolia Autonomous Region , Nei Mongol , San Diego , Collaborative Innovation Center , Chinese National Health Commission , Chinese Center , Flow Cytometry De Novo Software , National Institute For Communicable Disease , Key Laboratory For Infectious Disease Prevention , Beckman Coulter , Graphpad Software , Bd Facsdiva Software Version , Guyang County , Baotou City , State Key Laboratory , Infectious Disease Prevention , Infectious Diseases , National Institute , Communicable Disease Control , Disease Control , Graphpad Prism ,

Covid China: Staff at Wuhan lab admit 'devastating pandemics can occur' if viruses escape

In a 2,000-word article published in a scientific journal, professors from the Wuhan Institute of Virology laid out a series of recommendations to avoid spillovers - amid fears Covid leaked from the lab. ....

United States , United Kingdom , Comunidad Autonoma De Cataluna , South Korea , Simon Clarke , Donald Trump , Francis Collins , Li Wenliang , Shi Zheng Li , Profesor Zhiming , Tedros Adhanom Ghebreyesus , Jianguo Xu , Anthony Fauci , David Livermore , Peter Embarek , Jeremy Farrar , Chan Xia , Wei Jingsheng , Mike Farzan , China Centre For Disease , University Of Veterinary Medicine , United Nations , World Health Organisation , Anglia University , China National Health Commission , University Of Reading ,