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Molecular cage gives cryo-EM researchers new insights into cancer protein

Sandwiching wiggly proteins between two other layers allows scientists to get the most detailed images yet of a protein that’s key to the spread of ....

United States , Naoki Horikoshi , Kathleen Sakamoto , Greg Stewart , Kaiming Zhang , Ron Dror , Soichi Wakatsuki , Department Of Energy , American Cancer Institute , University Of Science , National Institutes Of Health , Stanford School Of Medicine , Lymphoma Society , Pediatric Cancer Research Foundation , Stanford University Schools Of Medicine , Maternal Child Health Research Institute , Stanford University , Technology Of China , National Accelerator Laboratory , Accelerator Laboratory , Stanford School , Stanford Professor Wah Chiu , National Institutes ,

Researchers probe secrets of natural antibiotic assembly lines

In two new papers, researchers used X-ray crystallography and cryogenic electron microscopy to reveal new details of the structure and function of ....

El Paso , United States , University Of Texas , Dillon Cogan , Chu Young Kim , Irimpan Mathews , Christopher Fromme , Kaiming Zhang , Chaitan Khosla , Saket Bagde , Department Of Energy , National Institutes Of Health , University Of Texas At El Paso , Cornell University , Office Of Science , Structural Molecular Biology Program , Stanford University , National Institute , National Accelerator Laboratory , Accelerator Laboratory , Wah Chiu , Cryo Electron Microscopy , Synchrotron Radiation Lightsource , National Institutes , General Medical ,

How cells avoid molecular assembly line mistakes

How cells avoid molecular assembly line mistakes
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Researchers gain insight into how cells avoid assembly-line mistakes

Stanford researchers use one of the most sophisticated structural biology techniques available to investigate how molecular assembly lines maintain ....

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Nanoparticle vaccine for COVID-19

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IMAGE: A schematic visualization of the ferritin nanoparticle with shortened coronavirus spike proteins, which is the basis of a SARS-CoV-2 vaccine candidate from Stanford.
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Credit: Duo Xu
Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza. But, within days of closing their campus lab space as part of COVID-19 precautions, they turned their attention to a vaccine for SARS-CoV-2, the virus that causes COVID-19. Although the coronavirus was outside the lab s specific area of expertise, they and their collaborators have managed to construct and test a promising vaccine candidate. ....

United States , Palo Alto , Chan Zuckerberg Biohub , Payton Weidenbacher , Abigail Powell , Shaogeng Tang , Peters Kim , Kaiming Zhang , Stanford Bio , Shanshan Li , Mrinmoy Sanyal , National Institutes Of Health , Wu Tsai Neurosciences Institute , Stanford Blood Center , Dk Ludwig Fund For Cancer Research , Damon Runyon Cancer Research Foundation , Maternal Child Health Research Institute , Stanford University , National Accelerator Laboratory , Ludwig Professor , Accelerator Laboratory , Biosafety Level , Tho Pham , Stanford Medicine , Wah Chiu , Wallenberg Bienenstock Professor ,