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Integrated structural biology provides new clues for cystic fibrosis treatment

Integrated structural biology provides new clues for cystic fibrosis treatment
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United States , Scott Blanchard , Jesper Levring , Rockefeller University , Jude Department Of Structural Biology , Jue Chen , Jude Department ,

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration. ....

Karol Fiedorczuk , Emily Henderson , Rockefeller University , Jue Chen , Cystic Fibrosis , Huntington 39s Disease , Protein Folding ,