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Next-Generation Sequencing Assays and Target Therapy Changing Outcomes in Childhood ALL

Researchers determined treatments developed over the past 10-15 years may quickly lead to a cure for childhood ALL who are not already in remission.

United statesRob pietersDivision of oncologyJude department of oncologyChildhood cancer researchStephen hungerPediatric oncologyHon puiJude departmentPhiladelphia chromosome positive

Risk-Stratified Pediatric ALL Treatment Improves Outcomes, Reduces Drug Exposure

Modifications to a pediatric ALL treatment protocol improved outcomes in IKZF1del, ETV6::RUNX1, and poor prednisone response ALL; and Down syndrome.

Rob pietersDutch childhood oncology groupInternational society of paediatric oncologyUniversity of utrechtInternational societyPaediatric oncologyPediatric oncologyDown syndromeDown syndrome associated

Five-year survival rate for children with acute lymphatic leukemia has increased: Study

The study results of the ALL-11 treatment protocol, led by researchers at the Princess Maxima Center, were published in the scientific Journal of Clinical Oncology.

Rob pietersPrincess maxima centerPaediatric cancerCute lymphatic leukaemiaTreatment protocolPrincess maxima centerSurvival ratesQuality of lifeScientific discoveriesLl 11 treatment protocolJournal of clinical oncologyFive year survival rateResearch studyUtch youngstersOdified treatment proceduresDisease recurrence

Five-year survival rate for children with acute lymphatic leukemia has increased: Study

Five-year survival rate for children with acute lymphatic leukemia has increased: Study
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The netherlandsRob pietersPrincess maxima centerBetween april

Five-year survival of children with acute lymphatic leukemia continues to increase

The five-year survival of all children with acute lymphatic leukemia (ALL) has continued to increase to 94%. This is evident from a study of 800 Dutch children. Within the study, modified treatment protocols for four subgroups were examined.

Rob pietersAcute lymphoblastic leukemia

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