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SOC Drugs Provide Strong Foundation For Effective Combinations in Hematologic Malignancies

Catherine C. Coombs, MD, discusses future directions for BTK inhibitors in chronic lymphocytic leukemia and combination therapies in myelofibrosis. ....

United States , Catherinec Coombs , Angelag Fleischmann , Naveen Pemmaraju , Joshuaf Zeidner , International Consensus Classification , School Of Medicine , Division Of Hematology , Department Of Medicine , World Health Organization , University Of California Irvine , Onclive Institutional Perspectives , California Irvine , New England Journal , Chapel Hill , International Consensus , Bcl2 Inhibitors , Btk Inhibitors , Chronic Lymphocytic Leukemia , Acute Myeloid Leukemia , Hematologic Malignancies , Combination Therapy , 2023 Ash Annual Meeting ,

Common QTc Formula Can Led to Wrong Chemo Decisions

A formula commonly used to calculate QT interval prolongation overestimates the risk and may be leading to inappropriate chemotherapy decisions. ....

United States , New Hampshire , Benjamin Starobin , Joshuaf Zeidner , Daniel Richardson , Kevin Kwaku , Bristol Myers Squibb , University Of North Carolina At Chapel Hill , Hitchcock Medical Center , National Institutes Of Health , Boston Scientific , University Of North Carolina Cancer Hospital , North Carolina , Chapel Hill , Dartmouth Hitchcock Medical Center , North Carolina Cancer Hospital , National Institutes , Alignant Neoplasia , Ecg Monitoring , Electrocardiogram Monitoring , Holter Monitoring , Antineoplastic Drug , Nti Cancer Agents , Physician Assistants ,

QTc Formula Affects Heart Rhythm Assessment, Chemotherapy Dose

Use of the wrong corrected QTc formula was associated with inappropriate changes in clinical management of patients with cancer. ....

Joshuaf Zeidner , National Center , University Of North Carolina , Translational Sciences , Terminology Criteria , Adverse Events , North Carolina , Cancer Hospital , Advancing Translational ,

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