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Postdoctoral Fellow in Cancer Biology job with Jolanta Grembecka, PhD, Professor

Postdoctoral Fellow in Cancer Biology job in Ann Arbor, Michigan with Jolanta Grembecka, PhD, Professor. Apply Today. ....

Ann Arbor , United States , Tomasz Cierpicki , Jolanta Grembecka , University Of Michigan , Department Of Pathology , Western Blotting ,

Menin Inhibitors Are One Among Other Improvements for Blood Cancers

Menin inhibitors for patients with AML have been one of many improvements within the blood cancer space this year, Lee Greenberger of the Leukemia and Lymphoma Society told CURE®. ....

United States , Jolanta Grembecka , Lee Greenberger , American Society Of Hematology , Lymphoma Society , Blood Cancer ,

Researchers develop first-in-class inhibitors against key leukemia protein

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IMAGE: An X-ray crystallography image showing an ASH1L inhibitor developed at U-M in complex with the protein.
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Credit: Grembecka / Cierpicki Labs
The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases. The ASH1L protein, however, has been challenging to target therapeutically.
Now a team of researchers led by Jolanta Grembecka, Ph.D., and Tomasz Cierpicki, Ph.D., from the University of Michigan has developed first-in-class small molecules to inhibit ASH1L s SET domain preventing critical molecular interactions in the development and progression of leukemia. ....

United States , Tomasz Cierpicki , Jolanta Grembecka , Nature Communications , Um Rogel Cancer Center , University Of Michigan , Michigan Medicine , Um Rogel Cancer , ஒன்றுபட்டது மாநிலங்களில் , இயற்கை தகவல்தொடர்புகள் , உம் ரோஜல் புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , மிச்சிகன் மருந்து , உம் ரோஜல் புற்றுநோய் ,