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Researchers set new resolution record for imaging the human eye

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IMAGE: The researchers customized this adaptive optics scanning light ophthalmoscope to improve the imaging resolution by strategically blocking light in various locations of the instrument. Using less light is an advantage.
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Credit: Johnny Tam, National Eye Institute
WASHINGTON Researchers have developed a noninvasive technique that can capture images of rod and cone photoreceptors with unprecedented detail. The advance could lead to new treatments and earlier detection for retinal diseases such as macular degeneration, a leading cause of vision loss.
We are hopeful that this technique will better reveal subtle changes in the size, shape and distribution of rod and cone photoreceptors in diseases that affect the retina, said research team leader Johnny Tam from the National Eye Institute. Figuring out what happens to these cells before they are lost is an important step toward developing earlier interventions to treat and prev ....

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NIH-led team sets new bar in retinal imaging

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IMAGE: The mosaic of cone and rod photoreceptor cells is shown by confocal imaging (left) and split detection.
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Credit: Johnny Tam, Ph.D., National Eye Institute
A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before. Published in
Optica, the researchers report how they improved imaging resolution by a third by selectively blocking the light used to image the eye. NEI is part of the National Institutes of Health.
The achievement is the latest in an evolving strategy to monitor cell changes in retinal tissue that, in turn, will help identify new ways to treat and prevent vision loss from diseases such as age-related macular degeneration, a leading cause of blindness in people age 65 and older. ....

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