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Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data

Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data
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United Kingdom , Stephen Oneill , Paul Charlton , Jonathanw Bartlett , Daiichi Sankyo , Rahul Mohan , Davidg Lugo Palacios , Richard Grieve , Ken Paterson , Dorothea Nitsch , Ewan Pearson , Richardj Silverwood , Jim Lewsey , Anirban Basu , Kamlesh Khunti , Stephen Evans , Eli Lilly , Orlagh Carroll , Amandai Adler , Anna Carnegie , Andrewh Briggs , Patrick Bidulka , Ianj Douglas , Boehringer Ingelheim , Healthcare Products Regulatory Agency , Office For National Statistics ,

Study Shows The Impact Of Minimum Unit Pricing On Deaths And Hospital Admissions

Today, Public Health Scotland (PHS) and The Lancet publish new evidence showing the impact of alcohol minimum unit pricing (MUP) on deaths and hospital admissions attributable to alcohol consumption. Carried out in collaboration with the University o ....

United Kingdom , Daniel Mackay , Jim Lewsey , Public Health Intelligence Adviser , University Of Glasgow , School Of Health , Professor Of Public Health Informatics , Public Health Scotland , Grant Wyper , Public Health Informatics , Medical Statistics ,

Comorbidity and health-related quality of life in people with a chronic medical condition in randomised clinical trials: An individual participant data meta-analysis

Author summary Why was this study done? ➢ The EuroQol-5 dimension (EQ-5D) and SF-36 are questionnaire-based tools that combine measures of physical and mental health into overall quality of life scores. These scores are used in randomised controlled trials of drug treatments to estimate how treatments affect quality of life. These estimates then inform decisions about which treatments should be offered to people with specific conditions. ➢ Multimorbidity, the presence of 2 or more conditions, makes diagnosis and treatment more complex and is associated with worse quality of life in some settings. ➢ People with multimorbidity are underrepresented in clinical trials, and little is known about whether and how multimorbidity changes quality of life in clinical trials. This makes it difficult for clinicians and clinical guideline developers to determine how results from clinical trials should be applied to people with multimorbidity. What did the researchers do and find? ➢ To ....

City Of , United Kingdom , Glasgow City , United States , Davidm Kent , Bruce Guthrie , Jim Lewsey , Elainew Butterly , Emma Mcintosh , Davida Mcallister , Peter Hanlon , Lauriej Hannigan , Nickyj Welton , Francess Mair , Anoopsv Shah , Effectiveness Center , Norwegian Institute Of Public Health , University Of Edinburgh , Bristol Medical School , Population Health Sciences , University Of York , University Of Bristol , Department Of Mental Disorders , Affiliation Usher Institute , University Of Glasgow , Affiliation Population Health Sciences ,

Minimum pricing 'effective' in reducing alcohol consumption

MINIMUM unit pricing - which was introduced in Wales in March 2020 - has been effective in reducing alcohol consumption in, according to a report. ....

United Kingdom , Maree Todd , Lucie Giles , Jim Lewsey , Public Health Scotland , Public Health Intelligence Principal , University Of Glasgow , School Of Health , Medical Statistics ,

Minimum pricing 'effective' in reducing alcohol consumption, study finds

Minimum pricing 'effective' in reducing alcohol consumption, study finds
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United Kingdom , Maree Todd , Lucie Giles , Jim Lewsey , Public Health Scotland , Public Health Intelligence Principal , University Of Glasgow , School Of Health , Medical Statistics ,