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Pirtobrutinib demonstrated promising efficacy and a tolerable safety profile in heavily pretreated patients with relapsed/refractory mantle cell lymphoma who received prior therapy with a covalent BTK inhibitor. ....
Eli Lilly and Company s drug Jaypirca has been granted FDA approval for the treatment of chronic lymphocytic leukemia and small lymphocytic lymphoma in patients. ....
Eli Lilly said the health regulator gave the new approval to the drug for the treatment of chronic lymphocytic leukemia (CLL), a type of cancer in which the bone marrow makes too many of certain white blood cells. Jaypirca was first given accelerated approval by the FDA on Jan. 27 for the treatment of mantle cell lymphoma. ....
Eli Lilly s drug Jaypirca has received a second approval from the US FDA for the treatment of chronic lymphocytic leukemia (CLL), adding to its previous approval for mantle cell lymphoma (MCL). ....
The phase 3 BRUIN CLL-314 trial evaluating the selective noncovalent BTK inhibitor pirtobrutinib vs the potent covalent BTK inhibitor ibrutinib is currently enrolling patients with chronic lymphocytic leukemia and small lymphocytic lymphoma who previously received treatment with non-BTK inhibitor therapy. ....