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Gene discovery could help prevent heart attacks


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IMAGE: Researcher Mete Civelek, PhD, of the University of Virginia School of Medicine s Department of Biomedical Engineering and UVA s Center for Public Health Genomics.
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Credit: Courtesy Civelek lab
Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease. In addition to identifying gene variants that influence risk, they found that one gene in particular appears to have a protective effect.
Doctors may be able to use the findings to identify people at high risk and to develop better treatments and preventative interventions. ....

United States , The Netherlands , Alanm Fogelman , Gerard Pasterkamp , Aaron Aguhob , Garyk Owens , Ngozi Akingbesote , Liang Guo , Rita Anane , Mohamad Navab , Juditha Berliner , Emily Farber , Arjan Boltjes , Minnau Kaikkonen , Jameson Hinkle , Aloke Finn , Johanlm Bjorkegren , Alisa Chen , Bruin Pharma , Gabrielf Alencar , Clintl Miller , Lijiang Ma , Suna Onengut Gumuscu , Innovation Programme , School Of Medicine , American Heart Association Postdoctoral Fellowship ,

UVA researchers identify genes that influence risk for common form of heart disease


UVA researchers identify genes that influence risk for common form of heart disease
Dec 10 2020
Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease. In addition to identifying gene variants that influence risk, they found that one gene in particular appears to have a protective effect.
Doctors may be able to use the findings to identify people at high risk and to develop better treatments and preventative interventions.
Current drugs for coronary artery disease treat the risk factors, such as cholesterol or hypertension. Our studies used a genetic approach to identify the mechanisms in the wall of the blood vessels where the disease actually develops.” ....

United States , The Netherlands , Alanm Fogelman , Gerard Pasterkamp , Aaron Aguhob , Garyk Owens , Ngozi Akingbesote , Liang Guo , Rita Anane , Mohamad Navab , Juditha Berliner , Emily Farber , Arjan Boltjes , Minnau Kaikkonen , Jameson Hinkle , Aloke Finn , Johanlm Bjorkegren , Alisa Chen , Bruin Pharma , Gabrielf Alencar , Clintl Miller , Lijiang Ma , Suna Onengut Gumuscu , Innovation Programme , School Of Medicine , American Heart Association Postdoctoral Fellowship ,