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African Genomes Could Aid HIV Infections

The findings suggest that CHD1L’s could provide treatment opportunities for individuals infected with HIV-1. ....

Jacques Fellay , Radomir Jovanovic , Wide Association Study , Evole Polytechnique Federale De Lausanne , Genome Wide Association Study , Chromodomain Helicase ,

Genome-wide study finds link between CHD1L gene and HIV control

"We searched for human genetic variation that associates with spontaneous control of HIV and identified a novel region in the genome that is only variable in populations of African ancestries," says Professor Jacques Fellay at EPFL's School of Life Sciences. ....

Jacques Fellay , Paul Mclaren , Megan Craig , Wide Association , Manjinder Sandhu At Imperial College London , School Of Life Sciences , Professor Jacques Fellay , Genome Wide Association Studies , Public Health Agency , National Microbiology Laboratory , Manjinder Sandhu , Imperial College , Global Health , Hiv 1 , Immune Response , Public Health ,

Gene variant in people of African origin helps control HIV, says study

Gene variant in people of African origin helps control HIV, says study
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South Africa , United Kingdom , Jacques Fellay , Paul Mclaren , School Of Life Sciences , University Of Cambridge , Chromodomain Helicase , Life Sciences , Public Health Agency , National Microbiology Laboratory , Daily Newsletter ,

Learning how to control HIV from African genomes

Learning how to control HIV from African genomes
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Paul Mclaren , Jacques Fellay , Manjinder Sandhu At Imperial College London , Wide Association , School Of Life Sciences , Professor Jacques Fellay , Genome Wide Association Studies , Public Health Agency , National Microbiology Laboratory , Manjinder Sandhu , Imperial College ,

Learning how to control HIV from African geno

A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. An international effort co-led by EPFL, Canada’s National Microbiology Laboratory, and Imperial College London, it paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities. ....

Stanford University , United States , Noord Holland , Comunidad Autonoma De Cataluna , San Francisco , South Africa , Free State , Eastern Cape , Reggio Emilia , Emilia Romagna , City Of , United Kingdom , Mariannek Degorter , Erico Johnson , Davidb Goldstein , Segun Fatumo , Miriam Walter , Ayeshaa Motala , Andrea Cossarizza , Jamesj Goedert , Gordon Dougan , Cheryla Winkler , Stevenm Wolinsky , Cristina Pomilla , Isobel Jarvis , Paolo Angelino ,