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CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism. ....

Cold Spring Harbor Laboratory , New York , United States , New York University , Cold Spring Harbor , Jen Pan , Feng Zhang , Neville Sanjana , Megan Craig , Alba Corman , Ivan Iossifov , Alexandra Nikish , Yang Zhou , Randyj Platt , Congyi Lu , Mcgill University , National Institutes Of Health , Brain Behavior Foundation , Montreal Neurological Institute , Simons Center , York Genome Center , Massachusetts Institute Of Technology , Simons Foundation For Autism Research , York University , Broad Institute , American Journal ,

Gene Editing Uncovers Genome-Autism Link in Human Cells

Gene Editing Uncovers Genome-Autism Link in Human Cells
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New York University , New York , United States , Cold Spring Harbor Laboratory , Jen Pan , Yang Zhou , Ivan Iossifov , Randy Platt , Neville Sanjana , Alexandra Nikish , Congyi Lu , Alba Corman , Feng Zhang , Broad Institute , Massachusetts Institute Of Technology , Montreal Neurological Institute , Mcgill University , Brain Behavior Foundation , York Genome Center , Simons Center , National Institutes Of Health , Simons Foundation For Autism Research , York University , American Journal , Human Genetics , New York Genome Center ,

Autism Causes, Symptoms, Diagnosis, Treatment, Prognosis

Autism is a neurodevelopmental disorder typically characterized by impaired social and communication skills combined with repetitive movements. ....

United States , Ivar Lovaas , Michael Ronemus , Ivan Iossifov , Siddharth Kharkar , Somer Dawson , Shakya Bhattacharjee , Glenys Dixon , Trupti Shirole , Emmaj Glasson , Andrew Bondy , Michael Wigler , Carol Bower , Exchange Communication System , Centre For Disease , Autism Society , Disease Control , American Journal , Illness During Pregnancy Leads , Psychologist Assess , Cognitive Abilities , Children With , Behavioral Treatment , Discrete Trial Teaching , Trial Teaching , Learning Programs ,

Father's Genetic Impact More On Siblings With Autism, Study Finds

The researchers found that when two or more children were diagnosed with autism, the siblings were more genetically similar to their father. ....

Ivan Iossifov , Cold Spring Harbor Laboratory , Health Day , York Cold Spring Harbor Laboratory , New York , Genetic Impact , Inherited Genes ,

Autism Research Indicated Father's Genetic Influence May Play a Greater Role Than Previously Thought

Scientists have long assumed that autism-related genetic mutations come from the mother. Researchers from Cold Spring Harbor Laboratory (CSHL) are challenging this belief with a recently published study. They say the father’s genes may actually play a greater role than previously thought, especially in families with multiple children on the autism spectrum. ....

Ivan Iossifov , Michael Wigler , Cold Spring Harbor Laboratory , Professor Michael Wigler , Asociate Professor Ivan Iossifov ,