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'Cutting the cable' between CD8+ T and T regulatory cells enhances checkpoint immunotherapy

Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. A multidisciplinary research team led by the University of California, Irvine has identified a new strategy that could enhance the therapeutic effectiveness of this therapy by targeting the communication between immune cells within the tumor.

Irvine-school , California , United-states , Irvine , Massachusetts , Francesco-marangoni , Shannon-geels , Multiscale-cell-fate-research , Uc-irvine-school-of-medicine , University-of-california , Saint-john-cancer-institute-in-santa-monica , Department-of-physiology-biophysics

'A broader view': How science communication is taught across the UC

'A broader view': How science communication is taught across the UC
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Monterey-bay , California , United-states , Berkeley , Irvine-school , Americans , Sheridon-kelly , Bristin-scalzo-jones , Denneal-jamison-mcclung , Santa-barbara , Kirsten-schwarz , Amanda-stansell

Circadian Clock Boosts Cancer Immunotherapy, UCI Study Finds

Circadian Clock Boosts Cancer Immunotherapy, UCI Study Finds
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United-states , Irvine-school , California , Orange-county , Irvine , American , Howard-gillman , Selma-masri , Uc-irvine-school-of-medicine , Department-of-biological-chemistry , Johnson , University-of-california

Study reveals circadian clock can be leveraged to enhance cancer immunotherapy

Study reveals circadian clock can be leveraged to enhance cancer immunotherapy
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Irvine , California , United-states , Irvine-school , Bridgetm-fortin , Selma-masri , Uc-irvine-school-of-medicine , University-of-california , Department-of-biological-chemistry , Nature-immunology , Bridget-fortin ,

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy
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Irvine , California , United-states , Irvine-school , Selma-masri , Johnson , Uc-irvine-school-of-medicine , University-of-california , Department-of-biological-chemistry , National-cancer-institute , V-foundation , Nature-immunology

UC Irvine study reveals circadian clock can be lev

UC Irvine study reveals circadian clock can be lev
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United-states , Irvine-school , California , Irvine , Orange-county , American , Howard-gillman , Selma-masri , Association-of-american-universities , University-of-california , Department-of-biological-chemistry , National-cancer-institute

UC Irvine study reveals circadian clock can b

UC Irvine study reveals circadian clock can b
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California , United-states , Irvine , Irvine-school , Orange-county , American , Howard-gillman , Selma-masri , Uc-irvine-school-of-medicine , National-cancer-institute , Johnson , Association-of-american-universities

A Doula's Patient Bond; Eye-Level Counsel; Translating Trust into Mandarin

Future physicians write about navigating cultural, political differences in health care essay contest.

Baltimore , Maryland , United-states , Irvine-school , California , Johns-hopkins-university , Puerto-rico , American , Claudia-rivera-barbeito , Furmans-mcdonald , Elina-kurkurina , Ella-eisinger

Lawsuit against Prop. 22 has its day in California Supreme Court

Lawsuit against Prop. 22 has its day in California Supreme Court
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LEGAL: Meter, Kantor, & Hopkins

LEGAL: Meter, Kantor, & Hopkins
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Andrew-kantor , Retirement-benefits-practice-group , California-western-school-of-law , Senior-associate , Retirement-benefits-practice , California-western-school , Irvine-school ,