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In stroke patients carrying CYP2C19 loss-of-function alleles that impede metabolism of clopidogrel, ticagrelor was more effective than clopidogrel at reducing recurrent stroke in the CHANCE-2 trial.

United statesS claiborne johnstonPhilipb gorelickChinese stroke associationTechnology of the people republic chinaNational scienceNorthwestern university feinberg school of medicineUniversity of texas at austinTechnology majorWorld stroke congressTechnology commissionMinistry of scienceMedscape medicalNew england journalNorthwestern university feinberg schoolHan chinese