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Safe and Strategic: Hyaluronic and Retinoic Acid Derivative Allays Aging and Acne April 1, 2021 Contact Author Paulina Orzol, Iva Doleckova, Jana Starigazdova, Gloria Huerta-Angeles and Vladimir Velebny, Contipro A.S., Dolni Dobrouc, Czech Republic
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Editor’s note:
The present article proposes a novel conjugate for the formulation of anti-aging and anti-acne cosmetics. In relation, readers are reminded that in the United States, anti-acne products are regulated as over-the-counter (OTC) drugs by the U.S. Food and Drug Administration (FDA). As such, formulas must follow the monograph if anti-acne treatment claims are to be made on products.
Retinoids are a group of active molecules comprising vitamin A and its natural and synthetic derivatives. Commonly used in cosmetic products, these lipophilic molecules bind to specific nuclear receptors that modulate the expression of genes involved in cellular proliferation and differentiation,