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Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient. ....

Santa Maria , Centro Hospitalar Universit , Rita Casc , Lobo Antunes , Taborda Barata , Emily Henderson , Department Of Neurosurgery , European Bioinformatics Institute , European Molecular Biology Laboratory United Kingdom , Portuguese Foundation For Science , Laboratory Of Neuropathology , Hospital Santa Maria , Cell Reports Medicine , Study First Author , Instituto De Medicina , Hospital Santa , Hospital De Santa Maria , Lisboa Norte , European Molecular Biology Laboratory , United Kingdom , Portuguese Foundation , Brain Metastases ,