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The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

Santa mariaCentro hospitalar universitRita cascLobo antunesTaborda barataEmily hendersonDepartment of neurosurgeryEuropean bioinformatics instituteEuropean molecular biology laboratory united kingdomPortuguese foundation for scienceLaboratory of neuropathologyHospital santa mariaCell reports medicineStudy first authorInstituto de medicinaHospital santa