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SDI pledges $1.5 million to Trine engineering expansion


ANGOLA — The Steel Dynamics Foundation Inc. has pledged $1.5 million toward Trine University’s engineering facility expansion, the university announced on Monday.
In honor of Steel Dynamics’ support, the new 40,000-square-foot expansion will be named the Steel Dynamics Inc. Center for Engineering and Computing.
Construction is expected to start in May or June with completion in about 12 months.
“The continual growth of our business requires a ready supply of well-trained engineers, and many who have contributed to the success of Steel Dynamics have come from Trine University,” said Mark Millett, president and CEO of Steel Dynamics Inc. “We are pleased to support this expansion in Trine’s facilities and programs, and look forward to the benefit this will provide, not only to SDI, but to industry throughout the region.” ....

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Studying chronic drug-induced liver toxicity in vitro


31 March 2021
The liver is one of the organs most susceptible to drug toxicity and drug induced liver injury (DILI). DILI is a major cause of drug attrition, with more than 750 FDA approved drugs known to have a degree of DILI risk. There are a number of strategies to de-risk DILI in drug discovery and, in recent years, focus has turned to human in vitro 3D liver models to better predict DILI in early and pre-clinical development. These models culture primary human liver cells, often in co-cultures, in a physiologically relevant environment allowing them to stay functional for extended periods of time.  This application assesses whether a microphysiological system (MPS), also known as Organ-on-a-Chip (OOC), in vitro liver model could be used to understand the detailed mechanistic aspects of liver toxicity. ....

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PerkinElmer, Inc.: PerkinElmer Further Expands Industry-Leading Signals Informatics Capabilities in Biologics Drug Discovery


PerkinElmer, Inc.: PerkinElmer Further Expands Industry-Leading Signals Informatics Capabilities in Biologics Drug Discovery
Interfaces with Geneious Prime and SnapGene software will assist in substantially reducing research cycle times and accelerating biologics and vaccine development
PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today announced its industry-leading documentation, workflow and decision making Signals informatics platform is being expanded to build on existing capabilities in the biologics drug discovery space. This comes through a collaboration with Insightful Science, a software company serving the global life sciences community.
With the collaboration, pharmaceutical and academic research teams can bring together the power of the PerkinElmer Signals platform with leading solutions from Insightful Science s Bioinformatics division. This includes the popular SnapGene and Geneious Prime software offerings that ....

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