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Prophylactic pancreatic stent plus indomethacin reduces rates of pancreatitis following endoscopic retrograde cholangiopancreatography

1. Post-ERCP pancreatitis was more common in the indomethacin alone group compared to indomethacin plus stent group. 2. The benefit of stent placement was prominent among patients at high risk for pancreatitis. Evidence Rating Level: 1 (Excellent) Study Rundown: In high-risk patients undergoing endoscopic retrograde cholangiopancreatography (ERCP), combining rectal indomethacin with prophylactic pancreatic stent placement ....

United States , Rating Level , Randomized Trial , Rectal Indomethacin , Between Sept , Acute Pancreatitis , Endoscopic Retrograde Cholangiopancreatography Ercp , Nonsteroidal Anti Inflammatory Drug Nsaid , Post Ercp Pancreatitis , Chronic Disease ,

Study shows how NSAIDs exacerbate C. difficile infections

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? ....

United States , Lily Ramsey , Josephp Zackular , Laboratory Medicine At Children Hospital Of Philadelphia , Science Advances , Joshua Soto Oca , Senior Author , Assistant Professor , Laboratory Medicine , Anti Inflammatory , C Diff , Ell Death , N Vitro , Inflammatory Bowel Disease ,