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Prophylactic pancreatic stent plus indomethacin reduces rates of pancreatitis following endoscopic retrograde cholangiopancreatography

1. Post-ERCP pancreatitis was more common in the indomethacin alone group compared to indomethacin plus stent group. 2. The benefit of stent placement was prominent among patients at high risk for pancreatitis. Evidence Rating Level: 1 (Excellent) Study Rundown: In high-risk patients undergoing endoscopic retrograde cholangiopancreatography (ERCP), combining rectal indomethacin with prophylactic pancreatic stent placement ....

United States , Rating Level , Randomized Trial , Rectal Indomethacin , Between Sept , Acute Pancreatitis , Endoscopic Retrograde Cholangiopancreatography Ercp , Nonsteroidal Anti Inflammatory Drug Nsaid , Post Ercp Pancreatitis , Chronic Disease ,

Expectant management of patent ductus arteriosus noninferior to early ibuprofen use

1. In this randomized controlled trial, expectant management of patent ductus arteriosus (PDA) in extremely premature infants required no active intervention unless complications arose. 2. Expectant management was shown to be noninferior to early ibuprofen in terms of preventing adverse neonatal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: PDA is a common complication of ....

Minute Medicine Inc , Rating Level , Absolute Risk Difference , Expectant Management , Nonsteroidal Anti Inflammatory Drug Nsaid , Patent Ductus Arteriosus Pda ,