Scientific advances and the end of tuberculosis: a report from the Lancet Commission on Tuberculosis thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.
Stages of tuberculosis disease can be delineated by radiology, microbiology, and symptoms,
but transitions between these stages remain unclear. In a systematic review and meta-analysis
of studies of individuals with untreated tuberculosis who underwent follow-up (34
cohorts from 24 studies, with a combined sample of 139 063), we aimed to quantify
progression and regression across the tuberculosis disease spectrum by extracting
summary estimates to align with disease transitions in a conceptual framework of the
natural history of tuberculosis.