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The natural history of untreated pulmonary tuberculosis in adults: a systematic review and meta-analysis

Stages of tuberculosis disease can be delineated by radiology, microbiology, and symptoms,
but transitions between these stages remain unclear. In a systematic review and meta-analysis
of studies of individuals with untreated tuberculosis who underwent follow-up (34
cohorts from 24 studies, with a combined sample of 139 063), we aimed to quantify
progression and regression across the tuberculosis disease spectrum by extracting
summary estimates to align with disease transitions in a conceptual framework of the
natural history of tuberculosis. ....

Slovak Republic , Hong Kong , Tamil Nadu , United States , United Kingdom , Orrego Puelma , Acta Tuberc Pneumol Scand , Schweizz Tuberk , Indianj Tuberc , Acta Tuberc Scand , International Union Against Tuberculosis Committee On Prophylaxis , Hong Kong Chest Service , Madras British Medical Research Council , British Medical Research Council , Tuberculosis Society Of Scotland , Bull World Health Organ , Us Department Of Health Human Services , Hong Kong Chest Service Tuberculosis Research Centre , Lancet Glob Health , Bull Int Union Tuberc , Tuberculosis Research Centre , Centers For Disease , World Health Organization , Delhi Police , Research Council , Princeton University Press ,