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This study examines whether the addition of bisoprolol to treatment of people with chronic obstructive pulmonary disease (COPD) at high risk of

United statesCity ofUnited kingdomSan diegoParticipantsthe bisoprololSanofi genzymeGraham devereuxAmerican thoracic society european respiratoryManchester biomedical research centreHealth services research unitScotlanda research ethics committeePragmatic research institute singaporeCare researchLothian respiratory managed clinical networkHull airway reflux questionnaireCentre for healthcare randomized trials