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Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial | Chronic Obstructive Pulmonary Disease | JAMA

This study examines whether the addition of bisoprolol to treatment of people with chronic obstructive pulmonary disease (COPD) at high risk of

United statesCity ofUnited kingdomSan diegoParticipantsthe bisoprololSanofi genzymeGraham devereuxAmerican thoracic society european respiratoryManchester biomedical research centreHealth services research unitScotlanda research ethics committeePragmatic research institute singaporeCare researchLothian respiratory managed clinical networkHull airway reflux questionnaireCentre for healthcare randomized trials

High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study

High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study
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United statesCenters for diseaseAmerican thoracic society european respiratoryClin epidemiolEduc todayRespir resAmerican thoracicEuropean respiratory societyVasc diffuse lung disRespir medComput assist tomogrThorac disDisease controlMortal wkly rep

Grifols Meets Enrollment Target in Phase 3 Study of Two Dose Regimens of Prolastin®-C in Patients with Emphysema Due to Alpha-1-Antitrypsin Deficiency

Grifols Meets Enrollment Target in Phase 3 Study of Two Dose Regimens of Prolastin®-C in Patients with Emphysema Due to Alpha-1-Antitrypsin Deficiency
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Comunidad autonoma de catalunaUnited statesGrifol prolastinGrifols prolastinSandra camprubiBlood instituteSpanish stock exchangeInvestors relations department sustainabilityNational heartEuropean respiratory societyAmerican thoracic society european respiratoryAmerican thoracic societyHome genetic health risk service alphaMedia press officeMeets enrollment targetTwo dose regimens

Those Who Smoke Heavily Have High Incidence of Undiagnosed COPD

About a third of participants in the COPDGene trial with a history of heavy smoking had undiagnosed COPD or abnormal spirometry warranting medication.

United statesAmerican thoracic society european respiratoryResearch councilGenetic epidemiologyHispanic whiteAmerican thoracicEuropean respiratoryMedical research council

Usual interstitial pneumonia as a stand-alone diagnostic entity: the case for a paradigm shift?

Usual interstitial pneumonia (UIP) is characterised by a distinctive morphological and radiological appearance that was considered the pathognomonic hallmark of idiopathic pulmonary fibrosis (IPF). However, this peculiar lung remodelling pattern is also seen in other fibrotic interstitial lung diseases, including hypersensitivity pneumonitis, and connective tissue diseases. In this Personal View, we advocate the designation of a UIP pattern as a single, discrete diagnostic entity, amalgamating its primary form and secondary processes in disorders such as hypersensitivity pneumonitis (hypersensitivity pneumonitis with UIP), rheumatoid arthritis (rheumatoid arthritis with UIP), and others.

United statesMashonaland eastUnited kingdomKing jrClin rheumatolRoy chowdhuryAmerican thoracic society european respiratoryEuropean respiratory society american thoracicEuropean respiratory societyAmerican thoracic societyAmerican thoracicArthritis rheumBone spineEuropean respiratoryRev respir medEnglj med