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New research uncovers biological drivers of h

<p>Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers led by investigators from <a href="https://brighamandwomens.org/" target=" blank">Brigham and Women&rsquo;s Hospital</a>, a founding member of the <a href="https://www.massgeneralbrigham.org/" target=" blank">Mass General Brigham</a> healthcare system, in collaboration with the <a href="http://broadinstitute.org/" target=" blank">Broad Institute of MIT and Harvard</a> and Stanford Medicine, combined multiple sequencing and experimental techniques to map the rela ....

United States , Philine Guckelberger , Shamsudheenk Vellarikkal , Jessem Engreitz Stanford , Nathan Cheng , Martins Taylor , Ramcharans Angom , Oscar Sias Garcia , Alex Bloemendal , Katherine Guo , X Rosa Ma , Tony Zeng , Debabrata Mukhopadhyay , Erics Lander , Helen Kang Stanford , Jesse Engreitz , Glen Munson , Vivians Lee Kim , Gavinr Schnitzler , Stephen Hinshaw , Rajat Gupta , Krishna Aragam , Tungh Nguyen , Ronghao Zhou , Hilaryk Finucane , Shi Fang ,