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Tumor mutations may not predict response to immunotherapy, study finds

The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical Center researchers reported in a retrospective study. ....

David-hsieh , Maishara-muquith , Ut-southwestern-medical-center , Caris-precision-oncology-alliance , Drug-administration , Caris , Haroldc-simmons-comprehensive-cancer-center , Division-of-hematology , Nature-cancer , Medical-center , Assistant-professor , Internal-medicine

Machine Learning Detects Axillary Lymph Node Metastasis in Breast Cancer

An international group of researchers from the UT Southwestern Medical Center developed a model by combining traditional MRI with artificial intelligence which helps to detect breast cancer metastases more accurately. ....

Dallas , Texas , United-states , University-of-texas-southwestern-medical-center , Eugenep-frenkel , Albert-montillo , Liqiang-wang , Basak-dogan , Dogan-polat , Keith-hulsey , Parkland-health , Breast-imaging-research

Tumor mutations may not predict response to immuno

The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a ....

Dallas , Texas , United-states , Zhao-zhu , Magdalena-espinoza , Maishara-muquith , Jakel-hamon , David-hsieh , Children-medical-center-research-institute , Leader-of-the-development , Caris , Haroldc-simmons-comprehensive-cancer-center

New AI tool to detect possible metastatic breast c

Researchers at UT Southwestern Medical Center have developed a novel artificial intelligence (AI) model to improve the detection of breast cancer metastasi ....

Dallas , Texas , United-states , Dogan-polat , Albert-montillo , Keith-hulsey , Eugenep-frenkel , Liqiang-wang , Basak-dogan , Haroldc-simmons-comprehensive-cancer-center , Breast-imaging-research , King-foundation

Cellular housekeeping shows a potential for lifespan and healthspan extension in mammals

Drugs acting through this mechanism might be expected to improve the health and prolong the lifespan of human beings ....

Beth-levine , Louis-beecherl-jr , Salwa-sebti , Charles-cameron-sprague , Orson-moe , Donaldw-seldin , Haroldc-simmons-comprehensive-cancer-center , Kidney-research , Howard-hughes-medical-institute-investigator , Autophagy-research , Internal-medicine , Charles-cameron-sprague-distinguished-chair