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Single-dose COVID-19 vaccine effective against variants, study says


In the three months since Johnson & Johnson’s COVID-19 vaccine received emergency use authorization from the U.S. Food and Drug Administration, more than 10 million Americans have received the vaccine, according to the Centers for Disease Control and Prevention. The single-shot viral vector vaccine developed in collaboration with Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch was authorized for use based on clinical trial data showing strong clinical efficacy against symptomatic COVID-19 in the United States, Latin America and South Africa.
In a new study published in Nature, Barouch, director of BIDMC’s Center for Virology and Vaccine Research, and colleagues report on the antibody and cellular immune responses generated by the Ad26.COV2.S vaccine against the original viral strain and against SARS-CoV-2 variants of concern. The team found that this vaccine induced immune responses against all the viral variants.   ....

United States , South Africa , United Kingdom , Jinyan Liu , Erican Borducchi , Sally Shin , Lisah Tostanoski , Frank Struyf , Caroline Atyeo , Macaya Douoguih , Kathryne Stephenson , Dirk Heerwegh , Katherine Mcmahan , Hanneke Schuitemaker , Dan Barouch , Hannahh Gray , Michelle Lifton , Aiquan Chang , Davidr Martinez , Abishek Chandrashekar , Harlan Robins , Jingyou Yu , Jerald Sadoff , Joseph Nkolola , Brian Kaplan , Catherine Jacob Dolan ,

Cell mapping expert receives HHMI diversity fellowship with eight years of support


Cell mapping expert receives HHMI diversity fellowship with eight years of support
Scott Lyon, Office of Engineering Communications
Feb. 18, 2021 1 p.m.
The Howard Hughes Medical Institute (HHMI) has named Princeton postdoctoral researcher Sofia Quinodoz a 2020 Hanna Gray Fellow, bolstering her study into how the structures within cells contribute to disease.
Quinodoz will receive up to $1.4 million over the next eight years, funding her bioengineering research at Princeton and granting her startup funds for an unspecified future role as a principal investigator. Quinodoz, whose family emigrated from Argentina in the mid-1980s, earned her bachelor s degree in molecular biology from Princeton in 2013. The HHMI fellowship connects her to a growing network of diverse, early career researchers who are tackling the most urgent problems in the life sciences. ....

Cliff Brangwynne , Hannahh Gray , Hannah Gray , Junek Wu , Melanie Mcreynolds , Aarone Lin , California Institute Of Technology , Lewis Sigler Institute For Integrative Genomics , Howard Hughes Medical Institute , Sofia Quinodoz , Gray Fellow , Gray Fellows , Lewis Sigler Institute , Integrative Genomics , California Institute , ஹன்னா சாம்பல் , மெலனி ம்க்ரெய்நொல்ட்ஸ் , கலிஃபோர்னியா நிறுவனம் ஆஃப் தொழில்நுட்பம் , லெவிஸ் சிகிலேர் நிறுவனம் க்கு ஒருங்கிணைந்த மரபியல் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , சாம்பல் சக , சாம்பல் கூட்டாளிகள் , லெவிஸ் சிகிலேர் நிறுவனம் , ஒருங்கிணைந்த மரபியல் , கலிஃபோர்னியா நிறுவனம் ,