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But regression of myocardial fibrosis wasn t tied to the small LVEF improvement observed in the PIROUETTE trial of pirfenidone in patients with heart failure with preserved ejection fraction.

United kingdomAmicus therapeuticsYork heart associationNational institute for health research united kingdomBoehringer ingelheimUnivar solutionsLilly allianceGuerbet laboratoriesRoche productsPuretech healthHeart failurePreserved left ventricular ejection fractionNew york heart associationNational instituteHealth researchRoche products limited