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What to Know About the Factor XIa Inhibitors on the Horizon

Graeme Hankey, MBBS, MD, delves into the potential to uncouple bleeding and thrombotic risk ....

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Brain Bleeds Double the Risk of Arterial Ischemic Events

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Survivors of intracerebral hemorrhage had three times the risk of ischemic stroke compared with the general population, and twice the risk of myocardial infarction (MI), an analysis of U.S. population-based cohort studies found.
In a study of nearly 48,000 participants that adjusted for various factors, intracerebral hemorrhage was associated with an increased risk for later arterial ischemic events (HR 2.3, 95% CI 1.7-3.1), ischemic stroke (HR 3.1, 95% CI 2.1-4.5), and MI (HR 1.9, 95% CI 1.2-2.9), reported Santosh Murthy, MD, MPH, of Weill Cornell Medicine in New York City, and colleagues.
In subgroup analyses, the increased risk was comparable among Black and white individuals, and independent of measured traditional vascular risk factors and use of antithrombotic medication. ....

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