Investigators at the National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK) have used a gene-constrained analysis to identify nine new Alzheimer’s disease (AD) risk genes that are possibly linked to the higher prevalence of AD in people with African ancestry. One of those genes, GNB5, regulates the stability of certain G protein-signaling proteins, which are activated by G protein-coupled receptors (GPCRs). The authors showed that mice with only one copy of Gnb5 developed more amyloid plaques and tau tangles than those with two copies.
Notice 2023-43 provides helpful guidance on additional types of failures that may be self-corrected including certain demographic failures and plan loan failures that were previously ineligible.
GPCRs play a key role in many important physiological processes which makes them an important class of drug targets; however, their biophysical properties have made many GPCRs. | April 12, 2023
Biotech Antiverse has successfully identified functional antibody clusters targeting two G-protein-coupled receptors (GPCRs), both displaying versatile binding profiles and nanomolar affinity. Click to read more.
LONDON and NEW YORK, Feb. 21, 2023 (GLOBE NEWSWIRE) OKYO Pharma Limited (LSE: OKYO; NASDAQ: OKYO) ("OKYO", "OKYO Pharma" or the "Company"), an ophthalmology-focused bio-pharmaceutical company which