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The Lancet Infectious Diseases: Largest seroprevalence study in the region finds number of people infected with SARS-CoV-2 in Iran may be higher than expected


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An analysis of the first wave of the epidemic in Iran in 8902 people suggests the overall proportion of people with SARS-CoV-2 antibodies in their blood - known as seroprevalence - may be higher than rates based on clinical cases alone, at around 17.1% seropositivity vs 0.6% based on modelling from previous studies, by end of April 2020.
However, seroprevalence varies widely between cities - with the highest estimates found in Rasht (72.6%) and the lowest in Sanandaj (1.7%) although some cities had small samples sizes.
Despite high seroprevalence in a few cities, a large proportion of population is still uninfected. The potential shortcomings of current public health policies should therefore be identified to prevent future epidemic waves in Iran. ....

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