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Study reveals a unique mode of cell migration on soft 'viscoelastic' surfaces


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Study reveals a unique mode of cell migration on soft ‘viscoelastic’ surfaces
Stanford engineers find that cancer cells exhibit a unique mode of migration on squishy materials, which are similar to biological tissues. In contrast, cell movement – a process central to cancer metastasis and other biological processes – is typically studied on very rigid materials.
By Allison Gasparini
Inside your body, cell movement plays a crucial role in many significant biological processes, including wound healing, immune responses and the potential spread of cancer.
“Most people don’t die from having a primary tumor,” said Kolade Adebowale, a graduate student in chemical engineering, and a member of the Chemical Biology Interface (CBI) graduate program in Chemistry, Engineering & Medicine for Human Health (ChEM-H) at Stanford University. “The problem is when cancer cells from the tumor ac ....

United States , Ovijit Chaudhuri , Hong Pyo Lee , Damien Garbett , Allison Gasparini , Sungmin Nam , Tobias Meyer , Georgea Winzer , Kolade Adebowale , Stanford Bio , National Cancer Institute , Stanford Chemistry Biology Interface Predoctoral Training Program , National Institutes Of Health , Wu Tsai Neurosciences Institute , National Science Foundation , Stanford Cancer Institute , University Of Pennsylvania , University Of Minnesota , Maternal Child Health Research Institute , Stanford University , American Cancer Society , Engineering Medicine For Human Health , Chemical Biology Interface , Human Health , Nature Materials , Katrina Wisdom ,