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Dupilumab Shows Potential as First Biologic for COPD Treatment

Data also show significant improvements in quality of life and respiratory symptoms in patients with evidence of type 2 inflammation who were treated with dupilumab. ....

Dupilumab Dupixent , George Yancopoulus , Chief Scientific Officer , Published March ,

Geisinger genetic data helps in discovery of obesity-related mutations


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Genetic data gathered through Geisinger’s MyCode Community Health Initiative has helped in the discovery of gene mutations associated with protection against obesity.
According to a media release, scientists from t he Regeneron Genetics Center found rate mutations of the GPR75 gene after analyzing “deidentified genetic and associated health data from 645,000 volunteers from the United Kingdom, United States and Mexico,” including some involved in the MyCode initiative.
Projections suggest more than one billion people worldwide will suffer severe obesity defined as having a Body Mass Index (BMI) of 35 or higher by 2030. The research found that “individuals who have at least one inactive copy of the GPR75 gene have lower BMI and, on average, tend to weigh about 12 pounds less and face a 54% lower risk of obesity than those without the mutation.” The protective mutations were in one of about every 3,000 people studied. ....

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